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DeCS
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Descriptor English:
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Synapsins
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Descriptor Spanish:
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Sinapsinas
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Descriptor Portuguese:
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Sinapsinas
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Synonyms English:
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Synapsin I
Synapsin II
Synapsin III
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Tree Number:
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D12.776.631.750
D12.776.744.840
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Definition English:
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A family of synaptic vesicle-associated proteins involved in the short-term regulation of NEUROTRANSMITTER release. Synapsin I, the predominant member of this family, links SYNAPTIC VESICLES to ACTIN FILAMENTS in the presynaptic nerve terminal. These interactions are modulated by the reversible PHOSPHORYLATION of synapsin I through various signal transduction pathways. The protein is also a substrate for cAMP- and CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASES. It is believed that these functional properties are also shared by synapsin II. |
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History Note English:
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1992; use SYNAPSINS (NM) 1981-1991
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Allowable Qualifiers English:
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Record Number:
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29796
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Unique Identifier:
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D016704
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Occurrence in VHL:
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Similar:
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DeCS
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